David A. Tuveson: search on Z-Library

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1

Pancreatic cancer

Kleeff, Jorg, Korc, Murray, Apte, Minoti, La Vecchia, Carlo, Johnson, Colin D., Biankin, Andrew V., Neale, Rachel E., Tempero, Margaret, Tuveson, David A., Hruban, Ralph H., Neoptolemos, John P.

Journal:

Nature Reviews Disease Primers

Year:

2016

Language:

english

File:

PDF, 6.80 MB

english, 2016

2

Cancer modeling meets human organoid technology

Tuveson, David, Clevers, Hans

Journal:

Year:

2019

Language:

english

File:

PDF, 977 KB

english, 2019

3

ROS in Cancer: The Burning Question

Chio, Iok In Christine, Tuveson, David A.

Journal:

Trends in Molecular Medicine

Year:

2017

Language:

english

File:

PDF, 2.54 MB

english, 2017

4

The Era of COVID-19 and the Rise of Science Collectivism in Cancer Research

Janowitz, Tobias, Tuveson, David A.

Journal:

Cancer Discovery

Year:

2020

File:

PDF, 463 KB

2020

5

Maximizing mouse cancer models

Frese, Kristopher K., Tuveson, David A.

Journal:

Nature Reviews Cancer

Year:

2007

Language:

english

File:

PDF, 832 KB

english, 2007

6

Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

Demetri, George D., von Mehren, Margaret, Blanke, Charles D., Van den Abbeele, Annick D., Eisenberg, Burton, Roberts, Peter J., Heinrich, Michael C., Tuveson, David A., Singer, Samuel, Janicek, Milos,

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 285 KB

english, 2002

7

Recapitulating human cancer in a mouse

Chin, Lynda, de Sauvage, Frederic, Egeblad, Mikala, Olive, Kenneth P, Tuveson, David, Weiss, William

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 308 KB

english, 2013

8

The Promise and Perils of Antioxidants for Cancer Patients

Phimister, Elizabeth G., Chandel, Navdeep S., Tuveson, David A.

Journal:

New England Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

9

The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1

Palm, Wilhelm, Park, Youngkyu, Wright, Kevin, Pavlova, Natalya N., Tuveson, David A., Thompson, Craig B.

Journal:

Year:

2015

Language:

english

File:

PDF, 5.13 MB

english, 2015

10

Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening

Hou, Shurong, Tiriac, Hervé, Sridharan, Banu Priya, Scampavia, Louis, Madoux, Franck, Seldin, Jan, Souza, Glauco R., Watson, Donald, Tuveson, David, Spicer, Timothy P.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

11

Securing the future of the clinician-scientist

Noble, Karen, Owens, Joanna, AndrÃ©, Fabrice, Bakhoum, Samuel F., Loi, Sherene, Reinhardt, Hans Christian, Tuveson, David, Swanton, Charles

Journal:

Year:

2020

Language:

english

File:

PDF, 783 KB

english, 2020

12

An shRNA silencing a non-toxic transgene reduces nutrient consumption and increases production of adenoviral vectors in a novel packaging cell

Lifu Wang, Xiaoguang Qi, Ruizhe Shen, Ying Sun, David A. Tuveson

Journal:

Journal of Cellular Physiology

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

13

A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with19F NMR spectroscopy

Tashinga E. Bapiro, Frances M. Richards, Mae A. Goldgraben, Kenneth P. Olive, Basetti Madhu, Kristopher K. Frese, Natalie Cook, Michael A. Jacobetz, Donna-Michelle Smith, David A. Tuveson, John R. Gri

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

14

10.1038/35074129

Johnson, Leisa, Mercer, Kim, Greenbaum, Doron, Bronson, Roderick T., Crowley, Denise, Tuveson, David A., Jacks, Tyler

Journal:

Year:

2001

Language:

english

File:

PDF, 378 KB

english, 2001

15

Translational medicine: Cancer lessons from mice to humans

Tuveson, David, Hanahan, Douglas

Journal:

Year:

2011

Language:

english

File:

PDF, 845 KB

english, 2011

16

Restoration of p53 function leads to tumour regression in vivo

Ventura, Andrea, Kirsch, David G., McLaughlin, Margaret E., Tuveson, David A., Grimm, Jan, Lintault, Laura, Newman, Jamie, Reczek, Elizabeth E., Weissleder, Ralph, Jacks, Tyler

Journal:

Year:

2007

Language:

english

File:

PDF, 776 KB

english, 2007

17

Modeling human lung cancer in mice: similarities and shortcomings

Tuveson, David A, Jacks, Tyler

Journal:

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

18

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

Tuveson, David A, Willis, Nicholas A, Jacks, Tyler, Griffin, James D, Singer, Samuel, Fletcher, Christopher DM, Fletcher, Jonathan A, Demetri, George D

Journal:

Year:

2001

Language:

english

File:

PDF, 225 KB

english, 2001

19

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Sunil R. Hingorani, Lifu Wang, Asha S. Multani, Chelsea Combs, Therese B. Deramaudt, Ralph H. Hruban, Anil K. Rustgi, Sandy Chang, David A. Tuveson

Journal:

Year:

2005

Language:

english

File:

PDF, 1.29 MB

english, 2005

20

KrasG12D and Smad4/Dpc4 Haploinsufficiency Cooperate to Induce Mucinous Cystic Neoplasms and Invasive Adenocarcinoma of the Pancreas

Kamel Izeradjene, Chelsea Combs, Melissa Best, Aarthi Gopinathan, Amary Wagner, William M. Grady, Chu-Xia Deng, Ralph H. Hruban, N. Volkan Adsay, David A. Tuveson, Sunil R. Hingorani

Journal:

Year:

2007

Language:

english

File:

PDF, 2.90 MB

english, 2007

21

Predictive in vivo animal models and translation to clinical trials

Natalie Cook, Duncan I. Jodrell, David A. Tuveson

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

22

BRAF as a potential therapeutic target in melanoma and other malignancies

David A Tuveson, Barbara L Weber, Meenhard Herlyn

Journal:

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

23

Targeting oncogene dependence and resistance

Sunil R Hingorani, David A Tuveson

Journal:

Year:

2003

Language:

english

File:

PDF, 84 KB

english, 2003

24

Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

David A Tuveson, Alice T Shaw, Nicholas A Willis, Daniel P Silver, Erica L Jackson, Sandy Chang, Kim L Mercer, Rebecca Grochow, Hanno Hock, Denise Crowley, Sunil R Hingorani, Tal Zaks, Catrina King, M

Journal:

Year:

2004

Language:

english

File:

PDF, 814 KB

english, 2004

25

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome

Kenneth P. Olive, David A. Tuveson, Zachary C. Ruhe, Bob Yin, Nicholas A. Willis, Roderick T. Bronson, Denise Crowley, Tyler Jacks

Journal:

Year:

2004

Language:

english

File:

PDF, 807 KB

english, 2004

26

Understanding Metastasis in Pancreatic Cancer: A Call for New Clinical Approaches

David A. Tuveson, John P. Neoptolemos

Journal:

Year:

2012

Language:

english

File:

PDF, 187 KB

english, 2012

27

Modelling oncogenic Ras/Raf signalling in the mouse

Florian A Karreth, David A Tuveson

Journal:

Current Opinion in Genetics & Development

Year:

2009

Language:

english

File:

PDF, 414 KB

english, 2009

28

C-Raf Inhibits MAPK Activation and Transformation by B-RafV600E

Florian A. Karreth, Gina M. DeNicola, Stephen P. Winter, David A. Tuveson

Journal:

Year:

2009

Language:

english

File:

PDF, 765 KB

english, 2009

29

Ras redux: rethinking how and where Ras acts

Sunil R Hingorani, David A Tuveson

Journal:

Current Opinion in Genetics & Development

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

30

Technologically advanced cancer modeling in mice

David A Tuveson, Tyler Jacks

Journal:

Current Opinion in Genetics & Development

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

31

RAS in cellular transformation and senescence

Gina M. DeNicola, David A. Tuveson

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

32

What We Have Learned About Pancreatic Cancer From Mouse Models

Pedro A. Pérez–Mancera, Carmen Guerra, Mariano Barbacid, David A. Tuveson

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 2.58 MB

english, 2012

33

ATP citrate lyase inhibition can suppress tumor cell growth

Georgia Hatzivassiliou, Fangping Zhao, Daniel E. Bauer, Charalambos Andreadis, Anthony N. Shaw, Dashyant Dhanak, Sunil R. Hingorani, David A. Tuveson, Craig B. Thompson

Journal:

Year:

2005

Language:

english

File:

PDF, 673 KB

english, 2005

34

Finding and Killing the CRABs of Pancreatic Cancer

Meredith E. Caldwell, David A. Tuveson

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

35

Su1907 Developing Drug Combinations to Co-Target Pancreatic Cancer and Its Supporting Stroma

Carapuça, Elisabete, Gemenetzidis, Emilios, Feig, Christine, Tuveson, David A., Kocher, Hemant

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 119 KB

english, 2014

36

Pancreatic stellate cells are immunosuppressive modulators in pancreatic ductal adenocarcinoma

Feig, Christine, Jones, James O., Wells, Richard J.B., Tuveson, David A., Fearon, Douglas T.

Journal:

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

37

Retinoic Acid–Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt–β-Catenin Signaling to Slow Tumor Progression

Froeling, Fieke E.M., Feig, Christine, Chelala, Claude, Dobson, Richard, Mein, Charles E., Tuveson, David A., Clevers, Hans, Hart, Ian R., Kocher, Hemant M.

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 11.02 MB

english, 2011

38

Developing drug combinations to co-target pancreatic cancer and its supporting stroma

Carapuca, Elisabete, Gemenetzidis, Emilios, Feig, Christine, Tuveson, David, Kocher, Hemant

Journal:

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

39

Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

Joensuu, Heikki, Roberts, Peter J., Sarlomo-Rikala, Maarit, Andersson, Leif C., Tervahartiala, Pekka, Tuveson, David, Silberman, Sandra L., Capdeville, Renaud, Dimitrijevic, Sasa, Druker, Brian, Demet

Journal:

Boston Medical and Surgical Journal

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

40

Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma

Saiyin, Hexige, Ardito-Abraham, Christine M, Wu, Yanhua, Wei, Youheng, Fang, Yuan, Han, Xu, Li, Jianang, Zhou, Ping, Yi, Qing, Maitra, Anirban, Liu, Jun O, Tuveson, David A, Lou, Wenhui, Yu, Long

Journal:

The Journal of Pathology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

41

Mouse Models of Pancreatic Ductal Adenocarcinoma

Ponz-Sarvise, Mariano, Tuveson, David A., Yu, Kenneth H.

Journal:

Hematology/Oncology Clinics of North America

Year:

2015

Language:

english

File:

PDF, 172 KB

english, 2015

42

Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma

Tournier, Cathy, Davies, Clare C., Harvey, Emma, McMahon, Raymond F.T., Finegan, Katherine G., Connor, Frances, Davis, Roger J., Tuveson, David A.

Journal:

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

43

P53 Mutations Change Phosphatidylinositol Acyl Chain Composition

Naguib, Adam, Bencze, Gyula, Engle, Dannielle D., Chio, Iok I.C., Herzka, Tali, Watrud, Kaitlin, Bencze, Szilvia, Tuveson, David A., Pappin, Darryl J., Trotman, Lloyd C.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.89 MB

english, 2015

44

Detecting and diagnosing ampullary neoplasms

Wang, Li-Fu, Hingorani, Sunil R., Tuveson, David A.

Journal:

Cancer Biology & Therapy

Year:

2004

Language:

english

File:

PDF, 909 KB

english, 2004

45

Model Organoids Provide New Research Opportunities for Ductal Pancreatic Cancer

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A., Engle, Dannielle D., Tuveson, David A., Clevers, Hans

Journal:

Molecular & Cellular Oncology

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

46

In Search of an Early Warning System for Pancreatic Cancer

Hingorani, Sunil R., Tuveson, David A.

Journal:

Cancer Biology & Therapy

Year:

2003

Language:

english

File:

PDF, 296 KB

english, 2003

47

Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis

Karreth, Florian, Tuveson, David A.

Journal:

Cancer Biology & Therapy

Year:

2004

Language:

english

File:

PDF, 417 KB

english, 2004

48

VAV1: A new target in pancreatic cancer?

DeNicol, Gina, Tuveson, David A.

Journal:

Cancer Biology & Therapy

Year:

2005

Language:

english

File:

PDF, 420 KB

english, 2005

49

Preclinical models of pancreatic ductal adenocarcinoma

Hwang, Chang-Il, Boj, Sylvia F, Clevers, Hans, Tuveson, David A

Journal:

The Journal of Pathology

Year:

2016

Language:

english

File:

PDF, 860 KB

english, 2016

50

Modeling Pancreatic Cancer with Organoids

Baker, Lindsey A., Tiriac, Hervé, Clevers, Hans, Tuveson, David A.

Journal:

Trends in Cancer

Year:

2016

Language:

english

File:

PDF, 1.97 MB

english, 2016